Association between biochemical parameters and pathological findings in the diagnosis of fatty liver in dairy cows

Association between biochemical parameters and pathological findings in the diagnosis of fatty liver in dairy cows

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The purpose of this study is to investigate the role of some serum parameters in the diagnosis of fatty liver in cattle with special attention to its degree and to determine the best cut point of these parameters in order to predict the occurrence of fatty liver.Blood and liver samples of 28 cows were taken at the time Pedal Arm Gear Set of slaughter.Serum concentrations of liver enzymes, bilirubin, protein, and lipid profile were determined and the ratio of blood lipids to HDL was calculated.BCS and age of the cows were also recorded.ROC statistical model was used to determine critical thresholds for fatty liver prediction.

As the severity of fatty liver increases, AST, GGT, cholesterol and HDL increases, and these can be used as a biomarker to identify severe and mild fatty liver.Also, the severity of the disease increases as the BCS decreases and age increases.ROC analysis showed that AST, GGT, protein, cholesterol to HDL, BCS and age are suitable for predicting the disease.The best cut-off point for predicting fatty liver was suggested as 55.05 IU/L for AST, 14 U/L for GGT, 6.

55 mg/dl for total protein and 3.18 for cholesterol to Pin and Rack Service Kit HDL ratio.The best cut point for BCS and age was 4.25 and 6.5 years, respectively.

The result showed that measurement of liver enzymes and lipid profile is of acceptable diagnostic importance in determining the degree of fatty liver in cows in field conditions and can be a suitable method to replace liver biopsy.